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KMID : 1011420150200040463
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Journal of Korean Ophthalmic Optics Society
2015 Volume.20 No. 4 p.463 ~ p.469
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Physical Properties of the Hydrogel Using Alginate
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Woo Chul-min
Heo Seong-In
Lee Hyun-Mee
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Abstract
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Purpose: A hydrogel including alginate and CaCl2 extracted from seaweed was manufactured, and their physical properties were investigated. Also, its applicability as contact lenses was examined.
Methods: A film-type sample used in this experiment was manufactured using 2-hydroxyethyl methacrylate (HEMA), which is the raw material of hydrogel contact lenses; azobisiobutyonitile (AIBN), which is an initiator and ethylenglycoldimethacrylate (EGDMA), which is a cross-linking agent. It was hydrated in a PBS solution for 24 hours, and an interpenetrating polymer network (IPN) was formed in 1% and 2% alginate and 1%, 3%, and 5% CaCl2 solutions for 24 hours, respectively.
Results: The measurement of the physical properties of the film after the IPN showed that the moisture content was 30.89~36.89%, the refractive index was 1.431~1.441, the contact angle was 62.98~80.45o,and the tensile strength was 2.378~4.215 (gf/mm2). Also, the physical properties hardly changed as the content of alginate increased, and the moisture content decreased as the content of CaCl2 increased. As a result of the IPN, the moisture content and contact angle decreased compared to those of basic HEMA, but the tensile strength increased. The tensile strength of the second IPN was higher than that of the first IPN. In the case of CaCl2, for the sample polymerized for 24 hours and the second IPN sample with 2% alginate, the contact angle decreased as the content of CaCl2 increased.
Conclusions: In this study, the tensile strength increased as the content of CaCl2 increased, and the wettability increased as a result of IPN of alginate and CaCl2. The hydrogel containing the alginate and CaCl2 was confirmed possible utilization as contact lens material.
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KEYWORD
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Alginate, Hydrogel, IPN, Contact Angle, Water Contents, Tensile Strength
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